Quest® Plus Gel

Recommended for late grazing season (fall), Quest® Plus Gel is the only dewormer that treats encysted small strongyles, in a single dose with broad-spectrum support that also can help treat tapeworms.

Benefits of Quest® Plus Gel

Using an effective dewormer, at the right time can help reduce parasitic resistance.1 Quest Plus Gel is the only equine dewormer that targets the most threatening parasites in a single dose. The primary active ingredient, moxidectin, is considered the parasite experts’ treatment of choice against small strongyles and is also effective against large strongyles (bloodworms), bots, pinworms, hairworms and stomach worms.1 Quest Plus Gel also includes a second active ingredient, praziquantel, which provides the expert-recommended late grazing season (fall) treatment against tapeworms, which may also present serious health threats to horses.2 Quest Plus Gel has been evaluated as safe for use in breeding and pregnant mares.

1 dose
Gel formula dissolves quickly on the tongue
SURE-DIAL syringe for accurate dosing
Treats up to 1,500 pounds

Effective broad-spectrum
treatment for late grazing season

With Quest Plus Gel you can help target the right parasites at the right time, during late grazing season (fall). For early grazing season (spring), learn more about our recommended dewormer Quest Gel.

Product Name Quest Plus GelZimecterin®†,
Zimecterin Gold®†,
Active ingredients Moxidectin & PraziquantelIvermectinIvermectin & PraziquantelFenbendazole5-Day Double-Dose Fenbendazole
Parasites Most threatening to horses Tapeworms
Adult Small Strongyles
Encysted Small Strongyle Larvae
Adult Large Strongyles
Migrating Large Strongyle Larvae
Added coverage Bots
Stomach Worms

†Compared to labels of Zimecterin®, Zimecterin Gold®, Eqvalan®, IverCare®, Duramectin, Bimectin®, EquiMAX®, Safe-Guard®, and Panacur®.
*Per the 2019 American Association of Equine Practitioners’ Internal Parasite Control Guidelines, there is widespread roundworm (ascarid) resistance (lack of efficacy) to macrocyclic lactones (moxidectin and ivermectn).
**Per the 2019 American Association of Equine Practitioners’ Internal Parasite Control Guidelines, multiple studies show widespread small strongyle (cyathostomin) resistance (lack of efficacy) to benzimidazoles (fenbendazole and oxibendazole).

Zimecterin, Zimecterin Gold, and Eqvalan are registered trademarks of Boehringer Ingelheim Animal Health, IverCare is a trademark of Farnam Companies Inc. Bimectin is a trademark of Bimeda Inc. EquiMAX is a trademark of Virbac. Safe-Guard is a trademark of Intervet Inc. or an affiliate. Panacur is a registered trademark of Merck Animal Health.

How to use Quest® Plus Gel

Treating your horse can be safe and effective by following the steps outlined in this short video.

Additional resources

Use our collection of resources to learn how Quest Plus Gel and other Zoetis Equine products can help your horse receive the best care possible.

Find the right dewormer treatment plan

The Zoetis product finder will help you determine the effective product to use at the most appropriate time of year to help maintain your horse’s health.

Related products

We provide a comprehensive range of equine dewormers to treat the most dangerous parasites for your horse’s life stages without over-deworming.

Multiple Parasites


Quest® Gel 


Recommended for early grazing season. The Quest Gel and Quest Plus Gel are the only dewormers that treat encysted small strongyles and bots in a single dose, with broad-spectrum support that also treats large strongyles (bloodworms), pinworms, hairworms and stomach worms. Easy gel formula dissolves on the tongue.

Roundworms in Foals


Strongid® Paste

(pyrantel pamoate)

Recommended for the essential treatment of roundworms (ascarids) in young foals at 2 to 3 months of age. Also effective against large strongyles (bloodworms) and pinworms in adult horses.

Roundworms in Foals


Anthelcide® EQ Paste


Recommended for the important treatment of roundworms (ascarids) in foals at 4 to 6 months of age and 1 month post-weaning.


Do not use QUEST Gel or QUEST PLUS Gel in foals less than 6 months of age or in sick, debilitated and underweight horses. Do not use in other animal species, as severe adverse reactions, including fatalities in dogs, may result. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.


  1. American Association of Equine Practitioners. Internal Parasite Control Guidelines. Accessed December 2022.
  2. Proudman CJ, French NP, and Trees AJ. Equine Veterinary Journal. 1998; 30(3):194-199.